On this date in 1519 Ferdinand Magellan set sail from Sanlúcar de Barrameda with about 270 men on his expedition to circumnavigate the globe.

Frye in “The Times of the Signs” in Spiritus Mundi:

[W]ith the voyages of Columbus, de Gama and Magellan, humanity as a whole began to realize that the earth was round, and to order their lives on that assumption.  Up till then, the centre of the world had been, as the word itself makes obvious, the Mediterranean, and the people who sat like frogs around a pool, in Plato’s phrase, on the shores of the sea in the middle of the earth.  But after 1492 the nations of the Atlantic sea-board began to realize that it was they who were now in the middle of the world. (66-7)